the spectrum of renaldiseasein iran a post-mortem study

in order to study the incidence and histopathological aspects of renal disease and its role in the mortality rate in iran, the protocols of 4463 autopsies, performed in the last 15 years at the tehran university hospitals were reviewed. among 4463 autopsies there were 861 cases (20 %) of various renal diseases including 282 cases (32.75 %) of disease of the interstitium, 176 cases (20.44 %) of renal lesions in tuberculous patients, 112 cases (13.0 i %) of vascular disease, 101 cases (i l73 %) of diseases of the glomeruli, 48 cases (5.57 %) of rheumatic carditis, 30 cases (3.48 %) of epithelial nephrosis, 78 cases (3.25 %) of non tuberculous amyloidosis, 28 cases (3.25 %) of congenital malformation, 20 cases (2.37 %) of non tuberculous diabetes, 13 cases (l51 %) of neoplastic disease, 10 cases (1.16 %) os septicemia, 8 cases (0.93 %) of eclampsia and 5 cases (0.58 %) of myelomatous kidney. the underlying diseases in 35 cases of nephrotic syndrome were: tuberculosis, ii cases (31 %); non-tuberculous amyloidosis, 6 cases (17 ;;,); chronic glomerulonephritis, 5 cases (14 %); chronic pyelonephritis, 3 cases (10 %); and acute pyelonephritis, one case. the kidney was severely affected in systemic amyloidosis in 64 cases.